英文psc是什么意思_pse分别代表什么意思

英文psc是什么意思_pse分别代表什么意思Cell-PLoc 2.0 an improved package of web-servers for predicting subcellular localization of proteins in

Cell-PLoc 2.0 an improved package of web-servers for predicting subcellular localization of proteins in various organisms英文文献资料.docVIP   Vol.2, No.10, 1090-1103 (2010)   Natural Science   /10.4236/ns.2010.   Cell-PLoc 2.0: an improved package of web-servers for   predicting subcellular localization of proteins in various   organisms   Kuo-Chen Chou , Hong-Bin Shen   1,2 1,2   1   2   Gordon Life Science Institute, 13784 Torrey Del Mar Drive, San Diego, CA 92130, USA; kcchou@   Institute of Image Processing & Pattern Recognition, Shanghai Jiaotong University, 800 Dongchuan Road, Shanghai, , China;   hbshen@   Received 5 August 2010; revised 8 September 2010; accepted 12 September 2010.   ABSTRACT   most important attributes. It can provide useful insight   about the function of the protein. It is also fundamental   to system biology because knowledge of the subcellu-   lar locations of proteins is indispensable for in-depth   understanding how the biological processes are regu-   lated by the intricate pathways at the cellular level   [1,2]. Particularly, the information of protein subcel-   lular location is very useful for identifying and priori-   tizing drug targets [3] during the process of drug de-   velopment.   Given an uncharacterized protein sequence, how can   we identify which subcellular location site it resides at?   Does the protein stay in a single subcellular location or   can it simultaneously exist in, or move between, two and   more subcellular location sites? Although the answers to   these questions can be determined by means of various   biochemical experiments, it is time-consuming and labo-   rious to acquire the desired information with experimen-   tal methods alone. Particularly, in the post-genomic age,   the number of newly found protein sequences has in-   creased explosively. For instance, in 1986 the Swiss-Prot   databank contained merely 3,939 protein sequence en-   tries, but the number has since jumped to 519,348 ac-   cording to the data released by the same databank on 10-   Aug-2010 (/sp

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